“Oral leukoplakia”
alludes to white keratotic plaques having excluded other known lesions and
etiologic factors except smoking. Due to the potential of malignant
transformation of this epithelial lesion, the purpose of the present
case-series was to determine the clinical and histologic precancerous features
of this lesion. The study was conducted at the oral medicine department at the
dental faculty, Kerman. Demographic, clinical and histopathologic
characteristics of biopsy proven oral leukoplakia cases were collected from the
documented records from 1999 to 2017 and registered in pre-designed charts.
Finally, out of the 47 patients, the consistency rate between the clinical and
histologic diagnosis of this lesion was 85.1%. The incidence of epithelial
dysplasia was 48.9% (38.3% mild, 8.5% moderate and 2.1% severe) whereas 53.2%
of the lesions were non-homogenous and 66% of the patients were smokers. Inasmuch
as dysplasia was reported in the approximately half of the cases, right
diagnosis of leukoplakia should be done by the dentist to prevent malignant
transformation. Proper understanding, recognising, identification and
differentiating this lesion are necessary for proper treatment.
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