A Review of Novel Methods of the Treatment of Cancer by Bacteria

Nowadays, the attention of nanoparticle-bearing bacteria as drug carrier is increasing with decreasing side effects in the treatment of cancer. Nanoparticles have better release and selectivity with less toxicity .Due to the cost-effectiveness of using bacteria and the conditions for the growth of drug delivery with nanoscale particles that is less in size and less toxic, it has been the goal of drug delivery. Targeted drug delivery with nano carriers is possible to control the location, timing, and speed of drug release. Anaerobic gram-negative bacteria such as Salmonella and E. coli and also beneficial intestinal bacteria, including bacterial Bifidium. have been used in the treatment of cancer that are in clinical trials of laboratory studies. In this review article, we are trying to draw up new related patterns that provide effective ways for research and future achievements by reviewing novel bacteria-targeted drug delivery methods.

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